Comment citer
Résumé
Introduction
HIV/AIDS is a global epidemic and remains a major public health concern. Although there is no cure, HIV infection has become a chronic condition thanks to effective treatment and care. Despite the beneficial effects of antiretroviral therapy (ART), metabolic abnormalities such as dyslipidaemia are increasingly reported. To date, no studies have been conducted in the Democratic Republic of the Congo on the lipid profile of people living with HIV (PLHIV).
Purpose
This study aimed to describe the lipid profile of PLHIV on antiretroviral therapy monitored in a hospital setting in Kinshasa.
Methods
A cross-sectional, descriptive, and analytical study was conducted. The study population comprised PLHIV on antiretroviral therapy, followed in a hospital setting in Kinshasa. Data were collected using a structured data collection form from eligible individuals who had provided informed consent. Lipid profile assessment was conducted on fasting samples.
Results
A total of 407 patients were included in the study, with a predominance of women (70.3%). The mean age was 50.2 ± 12.3 years. Total hypercholesterolaemia was observed in 51 patients (25.2%), LDL hypercholesterolaemia in 20 patients (9.9%), HDL hypocholesterolaemia in 68 patients (27.87%), and hypertriglyceridaemia in 29 patients (14.4%).
Conclusion
The lipid profile of patients on antiretroviral therapy in this study was marked by the presence of dyslipidaemia. Male sex, age over 50 years, hypertension, and alcohol consumption were associated factors in the development of lipid abnormalities among PLHIV.
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