Orapuh Journal | Journal of Oral & Public Health
CT angiography profile of lower extremity arterial diseases in an imaging center in Kinshasa, Democratic Republic of the Congo
Orap J, 7(4), 2026
PDF

Keywords

CT angiography
peripheral arterial disease
lower limb ischemia
vascular imaging
Congo

How to Cite

KABONGO KABUYA, C., MUKANGA, D., IYOTO, D., & MUKAYA TSHIBOLA, J. (2026). CT angiography profile of lower extremity arterial diseases in an imaging center in Kinshasa, Democratic Republic of the Congo . Orapuh Journal, 7(4), e1436. https://doi.org/10.4314/orapj.v7i4.36

Abstract

Introduction

The epidemiological transition in sub-Saharan Africa has led to an increasing burden of noncommunicable diseases, particularly cardiovascular diseases, including lower extremity peripheral arterial disease (PAD). However, imaging data remain limited in the Congolese context.

Purpose

To describe the CT angiography profile of lower extremity arterial diseases and to analyze the association between arterial anatomical variations and vascular pathologies in an imaging center in Kinshasa.

Methods

This was a retrospective, single-center observational analytical study including 124 CT angiography examinations performed between January 2015 and January 2020. Exhaustive sampling was used. Data were analyzed using SPSS version 21.0. Associations were assessed using the chi-square test and multivariate logistic regression. Results were expressed as odds ratios (ORs) with 95% confidence intervals (CIs). Statistical significance was set at p < .05.

Results

The mean age was 60 ± 11 years, with a male predominance. PAD (65.3%) and acute lower limb ischemia (25.8%) were the most frequent conditions. Anatomical variations were most frequent at the iliofemoral level (25.7%). In multivariate analysis, iliofemoral variations were significantly associated with PAD (OR = 11.90; 95% CI [3.23, 39.53]; p < .001) and acute ischemia (OR = 10.29; 95% CI [3.23, 41.79]; p < .001).

Conclusion

Lower extremity arterial diseases in Kinshasa are dominated by PAD and acute ischemia, both significantly associated with arterial anatomical variations. CT angiography is essential for accurate evaluation and therapeutic planning.

https://doi.org/10.4314/orapj.v7i4.36
PDF

References

Aboyans, V., Ricco, J.-B., Bartelink, M.-L. E. L., Björck, M., Brodmann, M., Cohnert, T., Collet, J.-P., Czerny, M., De Carlo, M., Debus, S., Espinola-Klein, C., Kahan, T., Kownator, S., Mazzolai, L., Naylor, A. R., Roffi, M., Röther, J., Sprynger, M., Tendera, M., & Tepe, G. (2018). 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery (ESVS). European Heart Journal, 39(9), 763–816. https://doi.org/10.1093/eurheartj/ehx095

Alessandro, N., Michele, A., Zaccagna, B., et al. (2011). Peripheral arterial occlusive disease: Diagnostic performance and effect on therapeutic management of 64-section CT angiography. Radiology, 261(3), 976–986. https://doi.org/10.1148/radiol.11110263

Bhatt, C. J., Patel, L., & Ariwala, N. (2011). 64-slice multidetector CT angiography in infrarenal aortic and lower limb vascular disease: Study of 100 cases. Gujarat Medical Journal, 66(1), 28–31.

Chatzizisis, Y. S., Coskun, A. U., Jonas, M., Edelman, E. R., Feldman, C. L., & Stone, P. H. (2007). Role of endothelial shear stress in the natural history of coronary atherosclerosis. Journal of the American College of Cardiology, 49(25), 2379–2393. https://doi.org/10.1016/j.jacc.2007.02.059

Conte, M. S., Bradbury, A. W., Kolh, P., White, J. V., Dick, F., Fitridge, R., Mills, J. L., Ricco, J. B., Suresh, K. R., Murad, M. H., Aboyans, V., Aksoy, M., Alexandrescu, V. A., Armstrong, D., Azuma, N., Belch, J., Bergoeing, M., Björck, M., Chakfé, N., & Cheng, S. (2019). Global vascular guidelines on the management of chronic limb-threatening ischemia. Journal of Vascular Surgery, 69(6S), 3S–125S.e40. https://doi.org/10.1016/j.jvs.2019.02.016

Gornik, H. L., Aronow, H. D., Goodney, P. P., Arya, S., Packard Brewster, L., Byrd, L., Chandra, V., Drachman, D. E., Eaves, J. M., Ehrman, J. K., Evans, J. N., Getchius, T. S. D., Gutiérrez, J. A., Hawkins, B. M., Hess, C. N., Ho, K. J., Jones, W. S., Kim, E. S. H., Kinlay, S., & Kirksey, L. (2024). 2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS guideline for the management of lower extremity peripheral artery disease. Circulation, 149(24), e1313–e1410. https://doi.org/10.1161/CIR.0000000000001251

Howard, D. P. J., Banerjee, A., Fairhead, J. F., Hands, L., Silver, L. E., & Rothwell, P. M. (2015). Population-based study of incidence, risk factors, outcome, and prognosis of ischemic peripheral arterial events: Implications for prevention. Circulation, 132(19), 1805–1815. https://doi.org/10.1161/CIRCULATIONAHA.115.016424

Kouakou Bouassa Davy Mélaine, B.-T. A. E., Kouassi, K. P. B., Akobé, J.-R. A., Ekra, S. A., Tanoh, K. E., et al. (2025). Apport de l’angioscanner dans l’artériopathie oblitérante des membres inférieurs en contexte ivoirien : Particularités épidémiologiques et lésionnelles. Health Research in Africa, 3(10), 48–52. https://doi.org/10.5281/hra.v3i10.7029

Lawrence, P. F., & Rubin, G. D. (2002). CT angiography of the arterial system. Radiologic Clinics of North America, 40(4), 729–749. https://doi.org/10.1016/S0033-8389(02)00011-2

Nadjingar, N., Martin, V. T., & Zhang, P. (2025). Increasing burden of lower extremity peripheral arterial disease in Sub-Saharan Africa, 1990–2021: Results from the Global Burden of Disease Study 2021. American Heart Journal Plus: Cardiology Research and Practice, 61, 100679. https://doi.org/10.1016/j.ahjo.2025.100679

Napoli, A., Anzidei, M., Zaccagna, F., Cavallo Marincola, B., Zini, C., Brachetti, G., Cartocci, G., Fanelli, F., Catalano, C., & Passariello, R. (2011). Peripheral arterial occlusive disease: Diagnostic performance and effect on therapeutic management of 64-section CT angiography. Radiology, 261(3), 976–986. https://doi.org/10.1148/radiol.11103564

Ota, H., Takase, K., Igarashi, K., Chiba, Y., Haga, K., Saito, H., & Takahashi, S. (2004). MDCT compared with digital subtraction angiography for assessment of lower extremity arterial occlusive disease: Importance of reviewing cross-sectional images. American Journal of Roentgenology, 182(1), 201–209. https://doi.org/10.2214/ajr.182.1.1820201

Shwaiki, O., Klena, J. W., & Abbara, S. (2021). Lower extremity CT angiography in peripheral arterial disease: From established approach to evolving technical developments. RadioGraphics, 41(2), 375–396. https://doi.org/10.1148/rg.2021200120

Song, P., Rudan, D., Zhu, Y., Fowkes, F. J. I., Rahimi, K., Fowkes, F. G. R., & Rudan, I. (2019). Global, regional, and national prevalence and risk factors for peripheral artery disease in 2015: An updated systematic review and analysis. The Lancet Global Health, 7(8), e1020–e1030. https://doi.org/10.1016/S2214-109X(19)30255-4

Tanaka, R., Yoshioka, K., Muranaka, K., et al. (2020). Subtraction CT angiography for evaluation of lower extremity arteries with severe calcification. European Radiology, 30(3), 1481–1489. https://doi.org/10.1007/s00330-019-06451-2

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.