Keywords
Haematological disorders
haemogram
Monkole Hospital
Democratic Republic of the Congo
How to Cite
Abstract
Introduction
Tuberculosis is an infectious disease that affects people around the world and is a major public health problem, with TB transmitted by humans and air. Some of the haematological disorders that are associated with tuberculosis are anemia, leukemia, and/or lymphopenia
Purpose
This study aimed to investigate hematological disorders in patients with tuberculosis.
Methods
This study was conducted at Monkole Hospital (Kinshasa, Democratic Republic of the Congo). A total of 50 tuberculosis patients were included in this case study. Blood samples were collected and analyzed to assess hematological parameters. Patients were randomly selected, and demographic data were gathered for in-depth analysis.
Results
The analysis revealed that anaemia was the sole hematological disorder observed in tuberculosis patients, with an average hemoglobin level of 8.6 g/dl. Examining erythrocyte indices, the predominant types of anaemia were normochromic normocytic anaemia and hypochromic normocytic anaemia.
Conclusion
This study confirmed that anaemia and leukopenia are common hematological disorders in patients with tuberculosis. The results of this study can have significant implications for the clinical management of tuberculosis patients. By gaining a better understanding of hematological disorders associated with tuberculosis, healthcare professionals can tailor their diagnostic and therapeutic approaches to enhance the quality of care provided to tuberculosis patients. This information can also guide future research into the hematological complications of tuberculosis, contributing
References
Amadou MLH, Abdoulaye O, Amadou O, Biraïma A, Kadri S, Amoussa AAK, Lawan IM, Tari L, Daou M, Brah S, Adehossi E. 2019. Profil épidémiologique, clinique et évolutif des patients tuberculeux au Centre Hospitalier Régional (CHR) de Maradi, République du Niger [Epidemiological, clinical and evolutionary profile of patients with tuberculosis at the Regional Hospital of Maradi, Republic of the Niger]. Pan Afr Med J., 33:120. French. Doi: 10.11604/pamj.2019.33.120.17715.
Azzeddine R, Elyassir F, Bourkadi JE. 2019. [Multifocal tuberculosis complicated by a macrophage activation syndrome: about two cases]. The Pan African medical journal 32:41.
Habibi B, Atmane A, Soualhi M, Bourkadi JE, Marc K, Zehraoui R, Benamor J. 2017.Troubles hématologiques observés au cours de la tuberculose multirésistante : à propos de 110 cas. Revue des Maladies Respiratoires, 34: A37-A38. https://doi.org/10.1016/j.rmr.2016.10.078
Khouloud B. 2022. Profils descriptive et épidémiologique des cas de tuberculose dans la wilaya de Guelma et étude des relations hôte-pathogène lors de l'infection par Mycobacterium tuberculosis Algérie: Université 8 mai 1945 Guelma 2022.
Lubala TK, Mutombo AM, Munkana AN, Manika MM. 2012. [Pulmonary tuberculosis revealed by thrombocytopenic purpura in children - about a clinical case observed in the pediatric ward of the University Hospital of Lubumbashi]. The Pan African medical journal, 12:75.
Moussaoui AE, Hammi S, Bourkadi JE. 2015. Les troubles hématologiques au cours de la tuberculose : à propos de 45 cas. Revue des Maladies Respiratoires 32:A 227.
Ngama CK, Muteya MM, Lukusha YI, Kapend SM, Tshamba HM, Makinko PI, Mulumba CM, Kapend a Kalala L. Profil épidémiologique et clinique de la tuberculose dans la zone de santé de Lubumbashi (RD Congo). 2014. [Clinical and epidemiological profile of tuberculosis in the health area of Lubumbashi (DR Congo)]. Pan Afr Med J, 17:70. French. Doi: 10.11604/pamj.2014.17.70.2445.
OMS. 2004. Combattre le SIDA, combattre la tuberculose, combattre maintenant : dossier d'information : tuberculose et VIH. www.unaids.org
OMS. 2022. Augmentation du nombre de cas de tuberculose et de décès dus à la maladie pendant la pandémie de COVID-19. 27 octobre 2022. Report No.
Sow KD, Yanogo P., Ndiaye M., Kane M., Sawadogo B., Otshudianjeka J., Laurent M., Diallo F., M., Ndri A., Meda N. 2021. Profil epedimiologique de la Tuberculose Senegal , 2009-2018. J.Inter Epidemiol Public Health, 4 (3): 12. Doi:10.11604/JIEPH.supp.2021.4.3.1125
Toujani S., Ben Salah N., Cherif J., Mjid M., Ouahchy Y., Zakhama H., Daghfous J., Beji M., N. Mehiri-Ben Rhouma N., Louzir B. 2015. La primo-infection et la tuberculose pulmonaire. Revue de Pneumologie Clinique, 71(2-3):73-82.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.