Abstract
Introduction
Appendicitis is one of the most common surgical emergencies worldwide, resulting from inflammation of the vermiform appendix attached to the cecum. Although pain is classically localised at McBurney’s point, the lack of consensus regarding its precise position, as highlighted by the studies of Karim and Naraysing, continues to fuel diagnostic and surgical debate. These uncertainties emphasise the need for a clearer understanding of the anatomical variations of the cecum and appendix to improve clinical accuracy and surgical outcomes.
Purpose
To describe and analyse anatomical variations of the cecum and vermiform appendix in order to assess their topographical and clinical implications. It is hypothesised that these variations influence the location of McBurney's point and may affect diagnostic accuracy and surgical planning. The study also aims to propose a standardised anatomical nomenclature for McBurney's point, which could enhance its clinical and surgical relevance.
Methods
A prospective descriptive study on the vermiform appendix was conducted between January 2017 and December 2022 in three hospitals in Kinshasa. The sample comprised 160 patients, selected by non-probability convenience sampling, who underwent midline infra-umbilical laparotomy. Intraoperative observations were collected, entered into Excel, and analysed using SPSS v20.0. Proportions were compared using the chi-square test, with statistical significance set at p < 0.05.
Results
In the study population (n = 160), females predominated (115; 71.9%, sex ratio = 2.56), and younger subjects were overrepresented, with the 11–20-year age group being the most frequent (60; 37.5%). The iliac position of the cecum was the most common (95; 59.4%), and a mobile cecum was observed in 124 cases (77.7%). The appendiceal base corresponded to the midpoint of McBurney’s line in 52 patients (32.5%). The appendix was mainly cylindrical (129; 80.6%), with a length between 7 and 12 cm in 86 patients (53.8%). The iliac position of the cecum predominated among patients aged 3–22 years (57; 35.6%), with a statistically significant difference (p = 0.023).
Conclusion
The study confirms the anatomical variability of the cecum and appendix. The cecum was predominantly mobile in the right iliac fossa, and the appendix, cylindrical and of medium length, often adopted a descending position. The appendicular base projected mainly on the umbilical–spinal line, justifying the use of the terms mid umbilical–spinal point and lateral umbilical–spinal point. These findings support promoting the laparoscopic approach to improve appendicitis management and reduce complications associated with anatomical variations.
References
Adesunkanmi, A. R., Ajayi, O. O., & Olayiwola, A. A. (2023). Appendicitis in sub-Saharan Africa: Trends, challenges, and opportunities. African Journal of Surgery, 41(2), 89–97. https://doi.org/10.1007/s12262-023-03657-2
Consorti, E. T., & Loren, B. (2013). Mobile cecum: An incidental finding. Journal of Surgical Case Reports, 2013(2), rjt008. https://doi.org/10.1093/jscr/rjt008
Duque, J. (2023). Proposed anatomical nomenclature for the traditional MacBurney point. Revue d'Anatomie Clinique, 15(2), 45–52.
GBD 2021 Appendicitis Collaborators. (2023). Global burden of appendicitis and its trends from 1990 to 2021: A systematic analysis. The Lancet Gastroenterology & Hepatology, 8(7), 623–635. https://doi.org/10.1016/S2468-1253(23)00045-7
GBD 2021 Appendicitis Collaborators. (2024). Global burden of appendicitis and age-specific trends, 1990–2021. The Lancet Gastroenterology & Hepatology, 9(9), 825–858. https://doi.org/10.1016/S2468-1253(24)00157-2
Gray, H. (2016). Gray’s Anatomy: The anatomical basis of clinical practice (41st ed.). Elsevier.
Karim, O. (2021). Radiological study of the parietal projection of the vermiform appendix. Journal de Radiologie Anatomique, 47(1), 12–20.
Kaya, B., Eris, C., & colleagues. (2022). Does the length matter in acute appendicitis for the perforation risk? Annals of Surgical Treatment and Research, 103(1), e1–e6. https://doi.org/10.4174/astr.2022.103.1.e1
Khanduri, S., Yadav, R., Khanduri, R., & colleagues. (2024). Computed tomography scan correlation of position of appendix. Indian Journal of Radiology and Imaging, 34(2), 105–113. https://doi.org/10.1055/s-0044-1781234
Kim, Y.-J., Lim, S., & Park, E. (2023). Anatomical location of the cecum in South Korean population using abdominal imaging. Korean Journal of Radiology, 24(7), 530–537. https://doi.org/10.3348/kjr.2023.0123
Mbaye, A., Ndiaye, M., & Diouf, A. (2022). Anatomical positioning of the cecum in Senegalese women: A CT-based study. West African Journal of Radiology, 14(2), 67–72. https://doi.org/10.4103/wajr.wajr_45_22
Mbwana, G., Mwangome, M., & Katana, S. (2024). Appendiceal position variations on CT in Tanzanian population: Implications for diagnosis. East African Medical Journal, 101(3), 150–158. https://doi.org/10.4103/eamj.2024.101.3.150
McBurney, C. (2022). Experience with early intervention on vermiform appendix conditions. The New York Medical Journal, 130(11), 678–684.
Mukenge, A., Bonyamina, J., & Mbusa, N. (2024). Surgical characteristics of appendectomies in the eastern region of the DRC. Journal de Chirurgie de l'Est-Africain, 12(2), 105–112.
Naar, L., Kim, P., Byerly, S., & colleagues. (2025). Clinical impact of appendiceal morphology on surgical outcomes and readmissions: Does size matter? Journal of Clinical Medicine, 14(16), 5635. https://doi.org/10.3390/jcm14165635
Naraysing, R. (2022). Caudal variability of appendicular projection: A barium enema study. Chirurgie Digestive Moderne, 20(3), 89–97.
Ndoye, M., Diouf, A., & Ba, A. (2018). Morphometric study of the vermiform appendix in adult Senegalese: Anatomical and clinical correlations. Journal of Morphological Sciences, 35(2), 45–50. https://doi.org/10.1016/j.jms.2018.02.004
Ngenzijakazi, P., Lumbala, P., & Kalombo, R. (2023). Epidemiological profile of appendicitis at the Butembo referral hospital. Journal Congolais de Chirurgie, 8(1), 45–52.
Omer, A., Ibrahim, M., & colleagues. (2024). Cecal volvulus in pregnancy: A diagnostic dilemma and management. Open Access Surgery, 17(3), 155–162. https://doi.org/10.2147/OAS.S414562
Rao, P., Daniels, J., & Freeman, S. (2022). Pelvic appendiceal location prevalence and diagnostic challenges in adult appendicitis. American Journal of Emergency Medicine, 50, 319–324. https://doi.org/10.1016/j.ajem.2021.09.032
Smith, J., Brown, E., & Johnson, R. (2024). Localization of MacBurney's point in clinical practice: A review. International Journal of Clinical Surgery, 28(2), 100–108. https://doi.org/10.1016/j.ijcs.2024.02.004
Sudagar, S., Kumar, A., & Ramesh, R. (2019). Anatomical variations of the vermiform appendix: A clinical study. International Journal of Anatomy and Research, 7(3), 6551–6556. https://doi.org/10.16965/ijar.2019.311
Tantia, O., Jain, M., & colleagues. (2023). CT evaluation of variations in positions and lengths of the normal appendix. Cureus, 15(8), e43982. https://doi.org/10.7759/cureus.43982
World Health Organization. (2023). Mortality and global health estimates: Appendicitis in the Democratic Republic of Congo. WHO Health Statistics Database. https://www.who.int/data

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